http://reposit.library.du.ac.bd:8080/xmlui/xmlui/handle/123456789/288 2026-04-07T01:56:30Z 2026-04-07T01:56:30Z Chowdhury, Ehsan Alam http://reposit.library.du.ac.bd:8080/xmlui/xmlui/handle/123456789/3903 2025-03-12T04:51:27Z 2025-03-12T00:00:00Z

Study of the efficacy of the Distribution of F-latency (DFL) in the diagnosis of cervical spondylosis Chowdhury, Ehsan Alam This thesis is submitted for the degree of Master of Philosophy.

2025-03-12T00:00:00Z Choudhury, Ehsan Alam http://reposit.library.du.ac.bd:8080/xmlui/xmlui/handle/123456789/972 2019-11-03T04:35:16Z 2014-04-02T00:00:00Z

Study of the efficacy of the Distribution of F-latency (DFL) in the diagnosis of cervical spondylosis Choudhury, Ehsan Alam Distribution of F-Latency (DFL) is a new parameter in peripheral nerve conduction measurement initiated by our extended group in Dhaka University which has been established to give a Distribution of Conduction Velocity (DCV) of motor nerve fibres in a peripheral nerve trunk as its approximate mirror image. An important application of this new technique, developed by the same group, is the detection of Cervical Spondylotic Neuropathy at an early stage through an evaluation of the pattern of DFL. Typically a single sharp peak corresponds to normalcy while double peak or a broad peak represents pathology. The definition of a broad peak was formalised through an earlier study by the extended group in collaboration with a group in Singapore. The current study is an exercise in validating DFL as a screening tool for CSN by comparing the data obtained from an extended pool of subjects (62 median nerves of 31 persons) against corresponding MRI findings through a double blind study. Subject selection was done randomly to fall under two age groups: 20 to 50 yrs, and above 50 yrs. A 1.5 Tesla MRI scanner and a home built Computerised EMG equipment were used for this study. The data were analysed with two slightly different approaches. In one, a mild compression of the spinal cord or a nerve root, as assessed through MRI, was counted as negative for CSN. In the other, the same was counted as positive. The sensitivities thus calculated for both the age groups combined (62 nerves) were 82% and 78% respectively while the specificities were 28% and 50% respectively. This suggested the consideration of abnormality for mild compression. Based on this, analyses for the lower age group (20-50 yrs, 44 nerves of 22 subjects) gave a sensitivity of 73% and a specificity of 50% while for the higher age group (>50 yrs, 18 nerves of 9 subjects), the sensitivity was 89%. The specificity could not be determined for this group as none came out as true negative and false positive. A surprising find of this study was the high prevalence (91%) of CSN in the younger age group, based on the MRI results, which needs further epidemiologic study. The present study establishes DFL on a stronger footing for assessment of cervical spondylotic neuropathy, whether due to spinal cord or nerve root compression. With further development, the performance is expected to improve making it more effective. . Being a non-invasive technique requiring virtually zero expenditure in consumables, it promises greater access to patients, and could be used for extensive prevalence study. The capability of DFL in detecting subclinical stages of CSN holds a promise as an awareness development tool alongside screening for prevalence of neuropathy. Those individuals who are diagnosed as positive for CSN and are still asymptomatic could be persuaded to make changes of lifestyle to lessen the chance of progression of their health condition. The main conclusion of the work is that DFL can not only be a cost effective screening test for CSN but also be instrumental in building awareness about preventive lifestyles in the general population (both young and old). The favourable results obtained here inspire confidence that this technique would prove its robustness and over time gain widespread acceptance. This dissertation submitted as a partial fulfilment of the requirements of the degree of M.Phil in Biomedical Physics & Technology under the University of Dhaka.

2014-04-02T00:00:00Z Khan, Ahamad Imtiaz http://reposit.library.du.ac.bd:8080/xmlui/xmlui/handle/123456789/970 2019-11-03T04:33:52Z 2015-05-31T00:00:00Z

Development of user friendly software in bangla for a pc based rural health monitor with option for telemedicine Khan, Ahamad Imtiaz Providing quality health service in rural areas is one of the major challenges for developing countries like Bangladesh. Even if infrastructures are provided, retaining qualified medical doctors in a village is almost impossible. The solution to this problem can be Telemedicine. Bangladesh has a good internet and mobile phone infrastructure spread almost all over the country which can be used to advantage. However, a proper telemedicine system requires PC connected digital diagnostic equipment at all rural centres. Importing such devices from the industrialized countries will be cost prohibitive. Besides, maintenance and repair will suffer contributing to frequent interruption of service. Looking towards a sustainable long term solution, our department at Dhaka University has already developed some basic diagnostic equipment the outputs of which are all digitized and interfaced to a PC. This includes, Stethoscope, X-ray viewer, Microscope, Colposcope and ECG (12 lead). Other information like temperature, blood pressure, weight, etc. of patients can be taken by a rural technician using low cost standard equipment and the operator can then type in the resulting values for integration with our telemedicine system. Necessary software was developed to integrate the diagnostic devices to the PC, to acquire and store the data into a PC at the rural centre and for transmission of relevant data over internet. For real time sound transmission we used Google Talk software which reproduced low frequency heart sounds well. Web based application was developed for our telemedicine solution. The purpose of this application is to maintain the whole system properly as its hub. Patient registration, request forwarding, patient acceptance, prescription preparation with mouse clicks using an updatable library of necessary phrases and drugs, report submission etc. can be done using this web based application. PHP and MySQL languages was used to develop this application. The goal of our task was to make it user friendly and appropriate for using in our rural areas. Graphical User Interface of both data acquisition software and web based application was developed in both English and Bangla languages. Bangla will make it easier for the rural operators to use it comfortably. The rural or semi-rural centres for telemedicine will be run by trained operators who will have basic knowledge and experience of using a PC. Operators will transmit data through internet to expert centres. Doctors from expert centre will talk to the patient and see the diagnostic test results, in real time if wanted. The doctor will finally provide a prescription, again through web based application. This dissertation submitted as a partial fulfilment of the requirements of the degree of M.Phil. in Biomedical Physics & Technology under the University of Dhaka.

2015-05-31T00:00:00Z